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(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid

Uses Sources
Product Name
(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid
CAS No.
181289-33-8
Chemical Name
(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid
Synonyms
methylhexanoic acid;INTERMEDIATE OF PREGABALIN;(3R)-3-(2-AMino-2-oxoethyl)-5-Methylhexanoic Acid;(r)-(-)-3-(2-amino-2-oxoethyl)-5-methylhexanoic acid;PGL-S-CMH acid;Pregabalin Impurity 94;Pregabalin IMpurity III;Isobutyl-glutamonoamide;PREGABALINS INTERMEDIATES 03;Pregabalin Carbamoyl Impurity
CBNumber
CB2854928
Molecular Formula
C9H17NO3
Formula Weight
187.24
MOL File
181289-33-8.mol
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(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid Property

Melting point:
128-133°C
Boiling point:
401.9±28.0 °C(Predicted)
Density 
1.080±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.68±0.10(Predicted)
color 
White to Off-White
CAS DataBase Reference
181289-33-8(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C175955
Product name
(R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoicacid
Packaging
5g
Price
$135
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA140304
Product name
(R)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic acid
Packaging
50g
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA140304
Product name
(R)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic acid
Packaging
25g
Price
$100
Updated
2021/12/16
Matrix Scientific
Product number
073067
Product name
R-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid
Purity
95+%
Packaging
25g
Price
$110
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0001191
Product name
(R)-(-)-3-(CARBAMOYMETHYL)-5-METHYLHEXANOIC ACID
Purity
95.00%
Packaging
1G
Price
$130.2
Updated
2021/12/16
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(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid Chemical Properties,Usage,Production

Uses

(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid is a useful chemical intermediate for manufacturing of the anticonvulsant drug, Pregabalin1, 2.

Sources

  1. https://quod.lib.umich.edu/a/ark/5550190.0011.a22?rgn=main;view=fulltext
  2. https://www.researchgate.net/publication/269660675_Synthesis_and_characterization_of_impurities_of_an_anticonvulsant_drug_Pregabalin

Chemical Properties

White Solid

Uses

An Impurity of the anti-convulsant (S)-Pregabalin (P704790).

(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid Suppliers

Canada 2 China 306 India 41 Spain 1 United Kingdom 3 United States 15 Global 368
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View Lastest Price from (R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid manufacturers

Chongqing Zhihe Biopharmaceutical Co., Ltd.
Product
(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid 181289-33-8
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
99
Supply Ability
20tons
Release date
2024-02-06
Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
R-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid 181289-33-8
Price
US $30.00/kg
Min. Order
1kg
Purity
99.7%
Supply Ability
200000kg
Release date
2024-04-24
Henan Fengda Chemical Co., Ltd
Product
(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid 181289-33-8
Price
US $35.00-1.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28

181289-33-8, (R)-(-)-3-Carbamoymethyl-5-methylhexanoic acidRelated Search:

EPA EC 2.3.2.2 ALTRENOGEST Hexamethylphosphoramide Ethyl 2-(Chlorosulfonyl)acetate Ethyl Hexanoate Phenylmethylsulfonyl fluoride Folic acid Glycine Citric acid 3-(Aminomethyl)-5-methylhexanoic acid Tris(hydroxymethyl)aminomethane Dimethyl sulfone 6-Aminocaproic acid 3-(Aminomethyl)-5-methylhexanoic acid Ascoric Acid 2-Hexenamide, 2-cyano-5-methyl- Hexanoic acid,3-(aminomethyl)-5-methyl-, (3R)-

  • (r)-(-)-3-(2-amino-2-oxoethyl)-5-methylhexanoic acid
  • (r)-(-)-3-carbamoymethyl-5-methylhexanoic acid
  • INTERMEDIATE OF PREGABALIN
  • (3R)-3-(2-AMino-2-oxoethyl)-5-Methylhexanoic Acid
  • (R)-3-(2-AMINO-2-OXOETHYL)-5-METHYLHEXANOIC ACID:99+%
  • 3-CarbaMoyl Mehyl-5-Methyl Hexanoic Acid
  • Pregabalin IMpurity III
  • Hexanoic acid,3-(2-aMino-2-oxoethyl)-5-Methyl-,(3R)-
  • (R)-3-(2-AMino-2-oxoethyl)-5-Methylhexanoic acid (R)-3-(2-AMino-2-oxoethyl)-5-Methylhexanoic acid
  • Pregabalin Carbamoyl Impurity
  • (R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid 181289-33-8
  • 181289-33-8 (R)-(-)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic acid
  • (±)-3-Carbamoylmethyl)-5-methyl hexanoic acid (CMH Acid)
  • methylhexanoic acid
  • Pregabalin Impurity III ((R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid)
  • Isobutyl-glutamonoamide
  • R-(-)-3-Carbamoylmethyl-5-hexanoic acid
  • (R)-(-)-3-carbamoy methyl)-5-methyl hexanoic acid(OR)
  • (R)-(-)-3-(CARBAMOYLMETHYL-5-METHYLMEXANOIC ACID
  • Pregabalin Impurity III (3-Carbamoymethyl-5-Methylhexanoic Acid)
  • (R)-3-(Carbamoylmethyl)-5-methylhex
  • Pregabalin 3-Carbamoylmethyl Impurity
  • PREGABALINS INTERMEDIATES 03
  • PGL-S-CMH acid
  • 3-Carbamoylmethyl-5-methyl hexanoic acid (Recimic)
  • R-(-)-3-(Carbamoylmethyl)-5-methylhexanoicaci
  • ?-(-)-3-(Carbamoyl methyl)-5-Methyl Haxanic Acid
  • R (-}3-CARSAMOYLMETIHYL-5-METHYLHEXANOIC ACID (RCMH)
  • 3-(2-Amino-2-oxoethyl)-5-methyl-(3S)-hexanoicacid
  • 3-(Carbamoyl)-5-Methyl Hexanoic Acid
  • R-(+)-3-(Carbamoylmethyl)-S- Methylhexanoic Acid
  • R-3-(Carbamoylmethyl)-5-Methylhexanoic Acid (Rcmh)
  • RCMH (R)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic Acid
  • Pregablin Impurity (RCMH acid)
  • Pregabalin Impurity 94
  • Isobutyl-glutamonoamide (R)-3-(2-amino-2-oxoethyl)-5-methylhexanoic acid
  • 181289-33-8
  • 181289-33-6
  • Aliphatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • intermidiate of Pregablin
  • Starting Raw Materials & Intermediates
  • 181289-33-8